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"Impacts of sex ratio Meiotic drive on stalk eyed flies"

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Please join the Biology Department and the Great Lakes Center for the seminar “Impacts of sex ratio Meiotic drive on stalk eyed flies.”, presented by Dr. Josie Reinhardt today at 3:00 p.m. in Bulger Communication Center 214. Attendees are welcome to arrive at 2:30 p.m. to enjoy coffee and cookies leading up to the seminar.

 

Research Seminar Abstract: Meiotic drivers are selfish genetic elements that violate the law of segregation, being passed to offspring at super-Mendelian ratios. In male stalk-eyed flies (Teleopsis dalmanni), an X-linked meiotic drive polymorphism drives at about 95% efficiency via a sperm-killing mechanism and is associated with reductions in length of male flies' sexual ornament (the eyestalk). We recently assembled and annotated a genome to map multiple inversions trapping variation on the drive X chromosome, and discovered a promising candidate gene for drive in a region of inversion overlap, a partial duplicate of a testes-expressed chromatin binding gene called JASPer. In addition, new whole genome sequencing evidence from a close relative indicates a likely shared origin of the drive X chromosome in these two species, despite earlier evidence suggesting distinct patterns of genetic divergence. Finally, we recently found evidence that drive male flies are more aggressive than their non-driving counterparts when matched for ornament size.

Submitted by: Nicholas Hahn